REVIEW PAPER
Isoprostanes – A novel major group of oxidative stress markers
 
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Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Toxicology and Carcinogenesis)
CORRESPONDING AUTHOR
Marta Czerska   

Nofer Institute of Occupational Medicine, Department of Toxicology and Carcinogenesis, Teresy 8, 91-348 Łódź, Poland
 
Int J Occup Med Environ Health 2016;29(2):179–190
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ABSTRACT
Isoprostanes are a recently discovered group of prostaglandin isomers. Results of previous studies suggest that they can be used as oxidative stress markers, because in a number of cardiovascular, pulmonary and neurological diseases their levels in biological samples considerably increase. It has been found that people suffering from diabetes, obesity, homozygous familial hypercholesterolemia, moderate hypercholesterolemia, and smokers have higher levels of isoprostanes in urine. The same refers to patients with asthma, Alzheimer disease and Down syndrome. This paper reviews the results of relevant studies.
eISSN:1896-494X
ISSN:1232-1087