Objectives: The purpose of this research is to explore the appropriate behaviors and characteristics of Patients for Patient Safety (PFPS) against the Chinese cultural background, especially the types and internal logical relationships of behaviors of PFPS. Material and Methods: In this research, Glazer’s methodology principle of the traditional grounded theory was adopted, and the methods of objective sampling, theoretical sampling and snowball sampling were employed. Considering the diversity of the interviewed subjects’ gender, age, professional title, qualification and demographic characteristics, representatives of hospital management staff, doctors, nurses, patients and their family members from different provinces and cities across the country were selected for semi-structured in-depth interviews to assess the behaviors of PFPS against the Chinese cultural background. In addition, some PFPS reports were collected from network media to supplement the interview data. All interviews were recorded and collated into Word text documents. Qualitative research data analysis software Nvivo 12 was used to sort out the collected data, and the theme was separated out through the strategy of substantive coding and theoretical coding. Results: In this research, the appropriate behaviors of PFPS were taken as the research content; 6 categories of appropriate behaviors of PFPS were separated out; and a model diagram of PFPS was constructed accordingly. Conclusions: A model diagram of the appropriate behaviors of PFPS against the Chinese cultural background was constructed to provide theoretical guidance for relevant research and practice. Int J Occup Med Environ Health. 2020;33(3):263–72