Occupational exposure to bisphenol A (BPA) in a plastic injection molding factory in Malaysia
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University of Malaya, Kuala Lumpur, Malaysia (Department of Pharmacology Faculty of Medicine)
SIRIM: Scientific and Industrial Research Institute of Malaysia, Selangor Darul Ehsan, Malaysia (Environment and Bioprocess Technology Centre)
Wided Kouidhi   

University of Malaya, Department of Pharmacology Faculty of Medicine, Jalan university, 50603 Kuala Lumpur, Malaysia
Online publication date: 2017-05-31
Int J Occup Med Environ Health 2017;30(5):743–750
Objectives: The purpose of this study has been to assess ambient bisphenol A (BPA) levels in workplaces and urine levels of workers and to establish a BPA database for different populations in Malaysia. Material and Methods: Urine samples were collected from plastic factory workers and from control subjects after their shift. Air samples were collected using gas analyzers from 5 sampling positions in the injection molding unit work area and from ambient air. The level of BPA in airborne and urine samples was quantified by the gas chromatography mass spectrometry – selected ion monitoring (GCMS-SIM) analysis. Results: Bisphenol A was detected in the median range of 8–28.3 ng/m³ and 2.4–3.59 ng/m³ for the 5 sampling points in the plastic molding factory and in the ambient air respectively. The median urinary BPA concentration was significantly higher in the workers (3.81 ng/ml) than in control subjects (0.73 ng/ml). The urinary BPA concentration was significantly associated with airborne BPA levels (ρ = 0.55, p < 0.01). Conclusions: Our findings provide the first evidence that workers in a molding factory in Malaysia are occupationally exposed to BPA. Int J Occup Med Environ Health 2017;30(5):743–750