ORIGINAL PAPER
Assessment of buccal mucosa genotoxicity in insecticide-exposed urban fumigators in Cali, Colombia
 
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1
Pontificia Universidad Javeriana Cali, Cali, Colombia (Faculty of Health Sciences, Department of Basic Health Sciences)
 
2
Pontificia Universidad Javeriana Cali, Cali, Colombia (Faculty of Health Sciences, Department of Public Health and Epidemiology)
 
3
University of Minnesota, Minneapolis, USA (Department of Anesthesiology)
 
 
Online publication date: 2024-01-23
 
 
Corresponding author
Elizabeth Londoño-Velasco   

Pontificia Universidad Javeriana Cali, Faculty of Health Sciences, Department of Basic Health Sciences, Calle 18 No. 118-250 Barrio Pance, Cali, Colombia
 
 
 
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ABSTRACT
Objectives: This study aimed to evaluate cytogenetic damage in the buccal mucosa of non-exposed subjects (N = 33) and insecticide-exposed fumigators (N = 31) in the urban area of Cali, Colombia. Material and Methods: Through a questionnaire sociodemographic data, anthropometric measurements, state of health, and lifestyle were collected. Buccal micronucleus cytome (BMCyt) assay was using for evaluate cytogenetic damage. Results: The study showed that all fumigators used adequate personal protective equipment (PPE) and had low alcohol consumption. The authors did not find significant differences in BMCyt biomarkers between the groups (p > 0.05). Multivariate analysis showed a 13% increase in micronucleus (MN) frequency for every year of increasing age (OR = 1.13, p = 0.029), and higher MN with the decrease in daily fruit consumption (OR = 4.71, p = 0.084), without statistical significance. Conclusions: The results between groups could be related to healthy habits and PPE use among the subjects. Int J Occup Med Environ Health. 2024;37(1)
eISSN:1896-494X
ISSN:1232-1087
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